Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

INTRODUCTION: Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets...

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Vydáno v:Cell Mol Life Sci
Hlavní autoři: Atanes, Patricio, Ruz-Maldonado, Inmaculada, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Al-Amily, Israa Mohammed, Salehi, Albert, Amisten, Stefan, Persaud, Shanta J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061145/
https://ncbi.nlm.nih.gov/pubmed/29455414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2778-z
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