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CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) represent a formidable tool for disease modeling, drug discovery, and regenerative medicine using human cells and tissues in vitro. Evolving techniques of targeted genome editing, specifically the CRISPR/Cas9 system, allow for the generation of cell lines bearing...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Protoc Stem Cell Biol
Egile Nagusiak: Gupta, Navin, Susa, Koichiro, Yoda, Yoko, Bonventre, Joseph V., Valerius, M. Todd, Morizane, Ryuji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060633/
https://ncbi.nlm.nih.gov/pubmed/30040245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpsc.50
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