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Brincidofovir (CMX001) Toxicity Associated with Epithelial Apoptosis and Crypt Drop Out in a Hematopoietic Cell Transplant Patient: Challenges in Distinguishing Drug Toxicity from GVHD

Brincidofovir (CMX001) is an oral agent with activity against double-strand DNA viruses undergoing clinical trials in immunocompromised patients. We report a patient clinically diagnosed with brincidofovir-related gastrointestinal (GI) toxicity and his histologic findings. A 2-year-old boy with medu...

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Detalhes bibliográficos
Publicado no:J Pediatr Hematol Oncol
Main Authors: Detweiler, Claire J, Mueller, Sarah B, Sung, Anthony D, Saullo, Jennifer L, Prasad, Vinod K, Cardona, Diana M
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059994/
https://ncbi.nlm.nih.gov/pubmed/29846280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000001227
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