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Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression

BACKGROUND: Deleted in Liver Cancer 1 (DLC1) is a tumor suppressor gene frequently deleted in cancer. However, DLC1 is not known to be deleted in angiosarcoma, an aggressive malignancy of endothelial cell derivation. Additionally, the physiologic functions of DLC1 protein in endothelial cells are po...

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Détails bibliographiques
Publié dans:J Natl Cancer Inst
Auteurs principaux: Sánchez-Martín, David, Otsuka, Atsushi, Kabashima, Kenji, Ha, Taekyu, Wang, Dunrui, Qian, Xiaolan, Lowy, Douglas R, Tosato, Giovanna
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059196/
https://ncbi.nlm.nih.gov/pubmed/29202196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx219
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