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DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis
Deleted in Liver Cancer 1 (DLC1) is a tumor suppressor gene deleted in many cancers, including angiosarcoma, an aggr malignancy of endothelial cell derivation. DLC1-deficiency in primary endothelial cells causes the loss of cell contact inhibition of growth through incompletely defined mechanisms. W...
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| 發表在: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8276116/ https://ncbi.nlm.nih.gov/pubmed/31409902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0944-x |
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