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A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma

Rhabdomyosarcoma (RMS), a cancer characterized by skeletal muscle features, is the most common soft tissue sarcoma of childhood. While low and intermediate-risk groups have seen improved outcomes, high-risk patients still face a 5-year survival of <30%, a statistic that has not changed in over 40...

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Bibliografske podrobnosti
izdano v:Mol Cancer Res
Main Authors: Slemmons, Katherine K., Crose, Lisa E.S., Riedel, Stefan, Sushnitha, Manuela, Belyea, Brian, Linardic, Corinne M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755394/
https://ncbi.nlm.nih.gov/pubmed/28923841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0004
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