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FGFR4 blockade exerts distinct anti-tumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma

PURPOSE: Rhabdomyosarcoma (RMS) is a malignancy with features of skeletal muscle, and the most common soft-tissue sarcoma of childhood. Survival for high risk groups is ~30% at 5 years and there are no durable therapies tailored to its genetic aberrations. During genetic modeling of the common RMS v...

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Detalhes bibliográficos
Main Authors: Crose, Lisa E.S., Etheridge, Katherine T., Chen, Candy, Belyea, Brian, Talbot, Lindsay J., Bentley, Rex C., Linardic, Corinne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713717/
https://ncbi.nlm.nih.gov/pubmed/22648271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3063
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