Načítá se...

BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells

Although inhibitors of bromodomain and extra terminal domain (BET) proteins show promising clinical activity in different hematologic malignancies, a systematic analysis of the consequences of pharmacological BET inhibition on healthy hematopoietic (stem) cells is urgently needed. We found that JQ1...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Haematologica
Hlavní autoři: Wroblewski, Mark, Scheller-Wendorff, Marina, Udonta, Florian, Bauer, Raimund, Schlichting, Jara, Zhao, Lin, Ben Batalla, Isabel, Gensch, Victoria, Päsler, Sarina, Wu, Lei, Wanior, Marek, Taipaleenmäki, Hanna, Bolamperti, Simona, Najafova, Zeynab, Pantel, Klaus, Bokemeyer, Carsten, Qi, Jun, Hesse, Eric, Knapp, Stefan, Johnsen, Steven, Loges, Sonja
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058788/
https://ncbi.nlm.nih.gov/pubmed/29567778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.181354
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!