Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes

Signaling through the αβT cell receptor (TCR) is a crucial determinant of T-cell fate and can induce two opposite outcomes during thymocyte development: cell death or survival and differentiation. To date, the role played by T-cell receptor in the oncogenic transformation of developing T cells remai...

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Publicat a:Haematologica
Autors principals: Gon, Stéphanie, Loosveld, Marie, Crouzet, Thomas, Potier, Delphine, Bonnet, Mélanie, Morin, Stéphanie O., Michel, Gérard, Vey, Norbert, Nunès, Jacques A., Malissen, Bernard, Roncagalli, Romain, Nadel, Bertrand, Payet-Bornet, Dominique
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058769/
https://ncbi.nlm.nih.gov/pubmed/29567770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.188359
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