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Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes
Signaling through the αβT cell receptor (TCR) is a crucial determinant of T-cell fate and can induce two opposite outcomes during thymocyte development: cell death or survival and differentiation. To date, the role played by T-cell receptor in the oncogenic transformation of developing T cells remai...
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| Опубликовано в: : | Haematologica |
|---|---|
| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Ferrata Storti Foundation
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6058769/ https://ncbi.nlm.nih.gov/pubmed/29567770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.188359 |
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