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Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors

Anti-mPEG/anti-human epidermal growth factor receptor 2 (HER2) bispecific antibodies (BsAbs) non-covalently bound to a docetaxel (DTX)-loaded mPEGylated lecithin-stabilized micellar drug delivery system (L(sb)MDDs) were endowed with active targetability to improve the chemotherapeutic efficacy of DT...

詳細記述

保存先:
書誌詳細
出版年:Drug Deliv
主要な著者: Su, Chia-Yu, Chen, Michael, Chen, Ling-Chun, Ho, Yuan-Soon, Ho, Hsiu-O, Lin, Shyr-Yi, Chuang, Kuo-Hsiang, Sheu, Ming-Thau
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058516/
https://ncbi.nlm.nih.gov/pubmed/29718725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1466936
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