Enhancement of tumor tropism of mPEGylated nanoparticles by anti-mPEG bispecific antibody for ovarian cancer therapy

Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby eliminating resident cancer cells for more effective therapeuti...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Lin, Wen-Wei, Cheng, Yi-An, Li, Chia-Ching, Ho, Kai-Wen, Chen, Huei-Jen, Chen, I.-J.u, Huang, Bo-Cheng, Liu, Hui-Ju, Lu, Yun-Chi, Cheng, Chiu-Min, Huang, Ming-Yii, Lai, Hung-Wen, Cheng, Tian-Lu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027450/
https://ncbi.nlm.nih.gov/pubmed/33828191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87271-2
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