Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

BACKGROUND: Developing a universal strategy to improve the specificity and sensitivity of PEGylated nanoaparticles (PEG-NPs) for assisting in the diagnosis of tumors is important in multimodality imaging. Here, we developed the anti-methoxypolyethylene glycol (mPEG) bispecific antibody (BsAb; mPEG ×...

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Udgivet i:J Nanobiotechnology
Main Authors: Cheng, Yi-An, Wu, Tung-Ho, Wang, Yun-Ming, Cheng, Tian-Lu, Chen, I-Ju, Lu, Yun-Chi, Chuang, Kuo-Hsiang, Wang, Chih-Kuang, Chen, Chiao-Yun, Lin, Rui-An, Chen, Huei-Jen, Liao, Tzu-Yi, Liu, En-Shuo, Chen, Fang-Ming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457265/
https://ncbi.nlm.nih.gov/pubmed/32854720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00680-9
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