On-demand PEGylation and dePEGylation of PLA-based nanocarriers via amphiphilic mPEG-TK-Ce6 for nanoenabled cancer chemotherapy

Rationale: PEGylation of nanocarriers could extend blood circulation time and enhance tumor accumulation via the enhanced permeability and retention (EPR) effect. Unfortunately, the PEG moiety suppresses tumor cell internalization of nanocarriers, resulting in limited therapeutic efficiency (known a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Zhu, Yueqiang, Chen, Chao, Cao, Ziyang, Shen, Song, Li, Laisheng, Li, Dongdong, Wang, Junxia, Yang, Xianzhu
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857060/
https://ncbi.nlm.nih.gov/pubmed/31754398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37128
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