mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)

mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA to PEG ratios are synthesized and used for encapsulation of recombinant human Growth hormone (rhGH). The structure and composition of the synthesized copolymers were analyzed by (1)H NMR and GPC techniques. Moreover, morphol...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ghasemi, Rohollah, Abdollahi, Mahdi, Emamgholi Zadeh, Elaheh, Khodabakhshi, Khosrow, Badeli, Ali, Bagheri, Hamed, Hosseinkhani, Saman
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026132/
https://ncbi.nlm.nih.gov/pubmed/29959339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28092-8
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