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mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)

mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA to PEG ratios are synthesized and used for encapsulation of recombinant human Growth hormone (rhGH). The structure and composition of the synthesized copolymers were analyzed by (1)H NMR and GPC techniques. Moreover, morphol...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Ghasemi, Rohollah, Abdollahi, Mahdi, Emamgholi Zadeh, Elaheh, Khodabakhshi, Khosrow, Badeli, Ali, Bagheri, Hamed, Hosseinkhani, Saman
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026132/
https://ncbi.nlm.nih.gov/pubmed/29959339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28092-8
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