mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)

mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA to PEG ratios are synthesized and used for encapsulation of recombinant human Growth hormone (rhGH). The structure and composition of the synthesized copolymers were analyzed by (1)H NMR and GPC techniques. Moreover, morphol...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ghasemi, Rohollah, Abdollahi, Mahdi, Emamgholi Zadeh, Elaheh, Khodabakhshi, Khosrow, Badeli, Ali, Bagheri, Hamed, Hosseinkhani, Saman
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026132/
https://ncbi.nlm.nih.gov/pubmed/29959339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28092-8
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