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HLA-DRB1–factor VIII binding is a risk factor for inhibitor development in nonsevere hemophilia: a case-control study

Development of anti-factor VIII (FVIII) inhibitory antibodies (inhibitors) is the most significant treatment complication of hemophilia A. Characteristics of the interaction between major histocompatibility complex (MHC) class II and FVIII peptides may influence FVIII antigen presentation to T cells...

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Kempton, Christine L., Payne, Amanda B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058228/
https://ncbi.nlm.nih.gov/pubmed/30037801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019323
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