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Drp1 phosphorylation by MAPK1 causes mitochondrial dysfunction in cell culture model of Huntington’s disease
Mitochondrial dysfunction is a major cytopathology in Huntington’s disease (HD), a fatal and inherited neurodegenerative disease. However, the molecular mechanisms by which the disease-causing gene, mutant Huntingtin (mtHtt), affects mitochondrial function remains elusive. This study aims to determi...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057844/ https://ncbi.nlm.nih.gov/pubmed/29397067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.01.114 |
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