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Time-Resolved Hydroxyl Radical Footprinting of RNA with X-Rays
RNA footprinting by hydroxyl radical cleavage provides ‘snapshots’ of RNA tertiary structure or protein interactions that bury the RNA backbone. Generation of hydroxyl radicals with a high-flux synchrotron X-ray beam provides analysis on a short timescale (5 ms to 100 ms), which enables the structur...
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| Pubblicato in: | Curr Protoc Nucleic Acid Chem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057793/ https://ncbi.nlm.nih.gov/pubmed/29927103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.52 |
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