Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim

The higher order structure (HOS) of biotherapeutics is a critical quality attribute that can be evaluated by nuclear magnetic resonance (NMR) spectroscopy at atomic resolution. NMR spectral mapping of HOS can be used to establish HOS consistency of a biologic across manufacturing changes or to compa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharm Biomed Anal
Prif Awduron: Brinson, Robert G., Ghasriani, Houman, Hodgson, Derek J., Adams, Kristie M., McEwen, Ian, Freedberg, Darón I., Chen, Kang, Keire, David A., Aubin, Yves, Marino, John P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057790/
https://ncbi.nlm.nih.gov/pubmed/28454057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2017.03.063
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg