PI3K-Mediated Blimp-1 Activation Controls B Cell Selection and Homeostasis

Activation of phosphoinositide 3-kinase (PI3K) signaling plays a central role in regulating proliferation and survival of B cells. Here, we tested the hypothesis that B cell receptor (BCR)-mediated activation of PI3K induces the terminal differentiation factor Blimp-1 that interferes with proliferat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Setz, Corinna S., Hug, Eva, Khadour, Ahmad, Abdelrasoul, Hend, Bilal, Mayas, Hobeika, Elias, Jumaa, Hassan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057491/
https://ncbi.nlm.nih.gov/pubmed/29996100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.035
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