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Important roles of PI3Kγ in osteoclastogenesis and bone homeostasis

G protein-coupled receptor-regulated PI3Kγ is abundantly expressed in myeloid cells and has been implicated as a promising drug target to treat various inflammatory diseases. However, its role in bone homeostasis has not been investigated, despite the fact that osteoclasts are derived from myeloid l...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kang, Heeseog, Chang, Woochul, Hurley, Marja, Vignery, Agnès, Wu, Dianqing
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919938/
https://ncbi.nlm.nih.gov/pubmed/20616072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001499107
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