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Important roles of PI3Kγ in osteoclastogenesis and bone homeostasis
G protein-coupled receptor-regulated PI3Kγ is abundantly expressed in myeloid cells and has been implicated as a promising drug target to treat various inflammatory diseases. However, its role in bone homeostasis has not been investigated, despite the fact that osteoclasts are derived from myeloid l...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919938/ https://ncbi.nlm.nih.gov/pubmed/20616072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001499107 |
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