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PI3K induces B-cell development and regulates B cell identity

Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that class IA PI3K-mediated signals induce the expression of the transcription fa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abdelrasoul, Hend, Werner, Markus, Setz, Corinna S., Okkenhaug, Klaus, Jumaa, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778048/
https://ncbi.nlm.nih.gov/pubmed/29358580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19460-5
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