Quantitative, multiplexed workflow for deep analysis of human blood plasma and biomarker discovery by mass spectrometry

Proteomic characterization of blood plasma is of central importance to clinical proteomics and particularly to biomarker discovery studies. The vast dynamic range and high complexity of the plasma proteome have, however, proven to be serious challenges and have often led to unacceptable tradeoffs be...

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Vydáno v:Nat Protoc
Hlavní autoři: Keshishian, Hasmik, Burgess, Michael W, Specht, Harrison, Wallace, Luke, Clauser, Karl R, Gillette, Michael A, Carr, Steven A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057147/
https://ncbi.nlm.nih.gov/pubmed/28749931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.054
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