NUDT15 Variants Cause Hematopoietic Toxicity with Low 6-TGN Levels in Children with Acute Lymphoblastic Leukemia

PURPOSE: We aimed to identify the impact of NUDT15 variants on thiopurine intolerance and 6-thioguanine nucleotide (6-TGN) levels in Korean children with acute lymphoblastic leukemia (ALL). MATERIALS AND METHODS: Genotyping of NUDT15 was tested in 258 patients with ALL registered at Samsung Medical...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Res Treat
Autors principals: Yi, Eun Sang, Choi, Young Bae, Choi, Rihwa, Lee, Na Hee, Lee, Ji Won, Yoo, Keon Hee, Sung, Ki Woong, Lee, Soo-Youn, Koo, Hong Hoe
Format: Artigo
Idioma:Inglês
Publicat: Korean Cancer Association 2018
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056957/
https://ncbi.nlm.nih.gov/pubmed/28903549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2017.283
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars