Susceptibility to thiopurine toxicity by TPMT and NUDT15 variants in Colombian children with acute lymphoblastic leukemia

Objective: This study aimed to correlate the genetic profile of the NUDT15 and TPMT genes with the side effects of the treatment of pediatric patients with acute lymphoid leukemia who were undergoing maintenance therapy at a tertiary care hospital in 2017. Methods: This was an analytical, longitud...

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Detalhes bibliográficos
Publicado no:Colombia Médica
Main Authors: Oscar Correa-Jimenez, Juan José Yunis, Adriana Linares-Ballesteros, Isabel Sarmiento-Urbina
Formato: Artigo
Idioma:Inglês
Publicado em: Universidad del Valle 2021
Assuntos:
Medicina
drug
children
mercaptopurine
pharmacogenetics
Acute lymphoid leukemia
Acesso em linha:https://www.redalyc.org/articulo.oa?id=28370069008
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