Susceptibility to thiopurine toxicity by TPMT and NUDT15 variants in Colombian children with acute lymphoblastic leukemia

Objective: This study aimed to correlate the genetic profile of the NUDT15 and TPMT genes with the side effects of the treatment of pediatric patients with acute lymphoid leukemia who were undergoing maintenance therapy at a tertiary care hospital in 2017. Methods: This was an analytical, longitud...

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Udgivet i:Colombia Médica
Main Authors: Oscar Correa-Jimenez, Juan José Yunis, Adriana Linares-Ballesteros, Isabel Sarmiento-Urbina
Format: Artigo
Sprog:Inglês
Udgivet: Universidad del Valle 2021
Fag:
Medicina
drug
children
mercaptopurine
pharmacogenetics
Acute lymphoid leukemia
Online adgang:https://www.redalyc.org/articulo.oa?id=28370069008
https://www.redalyc.org/journal/283/28370069008/
https://www.redalyc.org/journal/283/28370069008/html/
https://www.redalyc.org/journal/283/28370069008/28370069008.epub
https://www.redalyc.org/journal/283/28370069008/movil
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