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Transgelin-2 is a novel target of KRAS-ERK signaling involved in the development of pancreatic cancer

BACKGROUND: The KRAS mutation is the driving force of pancreatic ductal adenocarcinoma (PDAC). Downstream effectors of KRAS signal pathways are crucial to the development of PDAC. The purpose of this study was to investigate the relationship between KRAS mutation and transgelin-2. Transgelin-2 is hi...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Sun, Yan, Peng, Wenfang, He, Weiwei, Luo, Man, Chang, Guilin, Shen, Jiping, Zhao, Xiaoping, Hu, Yu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056937/
https://ncbi.nlm.nih.gov/pubmed/30041673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0818-z
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