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Beyond KRAS: Practical Molecular Targets in Pancreatic Adenocarcinoma

Pancreatic adenocarcinoma (PDAC) has a grim prognosis. Molecular and genomic analyses revealed that the striking majority of these tumors are driven by KRAS mutation, currently not amenable to targeted therapy. However, other driver mutations were found in a small fraction of patients. Herein we rep...

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Detalles Bibliográficos
Publicado en:Case Rep Oncol
Main Authors: Grinshpun, Albert, Zarbiv, Yonaton, Roszik, Jason, Subbiah, Vivek, Hubert, Ayala
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381925/
https://ncbi.nlm.nih.gov/pubmed/30792639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000496018
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