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Cytosolic Delivery of Multidomain Cargos by the N Terminus of Pasteurella multocida Toxin
The zoonotic pathogen Pasteurella multocida produces a 146-kDa modular toxin (PMT) that enters host cells and manipulates intracellular signaling through action on its Gα protein targets. The N terminus of PMT (PMT-N) mediates cellular uptake through receptor-mediated endocytosis, followed by the de...
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| 發表在: | Infect Immun |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056849/ https://ncbi.nlm.nih.gov/pubmed/29784857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00248-18 |
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