The C3 domain of Pasteurella multocida toxin is the minimal domain responsible for activation of G(q)-dependent calcium and mitogenic signaling

The large 1285-amino-acid protein toxin from Pasteurella multocida (PMT) is a multifunctional single-chain polypeptide that binds to and enters eukaryotic cells and acts intracellularly to promote G(q) and G(12/13) protein-dependent calcium and mitogenic signal transduction. Previous studies indicat...

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Hlavní autoři: Aminova, Leila R., Luo, Shuhong, Bannai, Yuka, Ho, Mengfei, Wilson, Brenda A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
For the Record
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327272/
https://ncbi.nlm.nih.gov/pubmed/18369188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.083445408
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