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Selective Membrane Redistribution and Depletion of Gα(q)-Protein by Pasteurella multocida Toxin
Pasteurella multocida toxin (PMT), the major virulence factor responsible for zoonotic atrophic rhinitis, is a protein deamidase that activates the alpha subunit of heterotrimeric G proteins. Initial activation of G alpha-q-coupled phospholipase C-beta-1 signaling by PMT is followed by uncoupling of...
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| Udgivet i: | Toxins (Basel) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4999849/ https://ncbi.nlm.nih.gov/pubmed/27490568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8080233 |
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