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Application of intact cell-based NFAT-β-lactamase reporter assay for Pasteurella multocida toxin-mediated activation of calcium signaling pathway

Pasteurella multocida toxin (PMT) stimulates and subsequently uncouples phospholipase C β1 (PLCβ1) signal transduction through its selective action on the alpha subunit of the Gq protein. Here, we describe the application of an NFAT-β-lactamase reporter assay as a functional readout for PMT-induced...

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Bibliografski detalji
Glavni autori: Luo, Shuhong, Ho, Mengfei, Wilson, Brenda A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681244/
https://ncbi.nlm.nih.gov/pubmed/18190943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2007.11.013
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