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SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas

Currently available SMO targeted therapies in patients with basal cell nevus syndrome (BCNS) are associated with substantial tumor recurrence and clinical resistance. Strategies bypassing SMO and/or identifying additional downstream components of the Hedgehog (Hh) pathway could provide novel anti-tu...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Kim, Arianna L., Back, Jung Ho, Chaudhary, Sandeep C., Zhu, Yucui, Athar, Mohammad, Bickers, David R.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056318/
https://ncbi.nlm.nih.gov/pubmed/29550418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.01.040
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