SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas

Currently available SMO targeted therapies in patients with basal cell nevus syndrome (BCNS) are associated with substantial tumor recurrence and clinical resistance. Strategies bypassing SMO and/or identifying additional downstream components of the Hedgehog (Hh) pathway could provide novel anti-tu...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Kim, Arianna L., Back, Jung Ho, Chaudhary, Sandeep C., Zhu, Yucui, Athar, Mohammad, Bickers, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056318/
https://ncbi.nlm.nih.gov/pubmed/29550418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.01.040
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