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Metformin, an anti-diabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway
The biguanide metformin is widely used for the treatment of type II diabetes. Its anti-proliferative and pro-apoptotic effects in various tumor cells suggest its potential candidacy for cancer chemoprevention. Here we report that metformin significantly inhibited human epidermoid A431 tumor xenograf...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476735/ https://ncbi.nlm.nih.gov/pubmed/22540890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2012.01165.x |
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