Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

Obesity is associated with colon cancer pathogenesis, but the underlying mechanism is actively debated. Here, we confirm that diet-induced obesity promotes tumor growth in two murine colon cancer models and show that this effect is reversed by an orally administered controlled-release mitochondrial...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Wang, Yongliang, Nasiri, Ali R., Damsky, William E., Perry, Curtis J., Zhang, Xian-Man, Rabin-Court, Aviva, Pollak, Michael N., Shulman, Gerald I., Perry, Rachel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056247/
https://ncbi.nlm.nih.gov/pubmed/29972790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.008
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