Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

Obesity is associated with colon cancer pathogenesis, but the underlying mechanism is actively debated. Here, we confirm that diet-induced obesity promotes tumor growth in two murine colon cancer models and show that this effect is reversed by an orally administered controlled-release mitochondrial...

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Publicat a:Cell Rep
Autors principals: Wang, Yongliang, Nasiri, Ali R., Damsky, William E., Perry, Curtis J., Zhang, Xian-Man, Rabin-Court, Aviva, Pollak, Michael N., Shulman, Gerald I., Perry, Rachel J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056247/
https://ncbi.nlm.nih.gov/pubmed/29972790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.008
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