Cell Type–Specific Quantification of Telomere Length and DNA Double-strand Breaks in Individual Lung Cells by Fluorescence In Situ Hybridization and Fluorescent Immunohistochemistry

Telomeres are small repetitive DNA sequences at the ends of chromosomes which act as a buffer in age-dependent DNA shortening. Insufficient telomere repeats will be recognized as double-strand breaks. Presently, it is becoming more evident that telomere attrition, whether or not caused by mutations...

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Bibliografski detalji
Izdano u:J Histochem Cytochem
Glavni autori: van Batenburg, Aernoud A., Kazemier, Karin M., Peeters, Ton, van Oosterhout, Matthijs F. M., van der Vis, Joanne J., Grutters, Jan C., Goldschmeding, Roel, van Moorsel, Coline H. M.
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2018
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055261/
https://ncbi.nlm.nih.gov/pubmed/29529386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155418761351
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