Telomerase Reverse Transcriptase Polymorphism rs2736100: A Balancing Act between Cancer and Non-Cancer Disease, a Meta-Analysis

The enzyme telomerase reverse transcriptase (TERT) is essential for telomere maintenance. In replicating cells, maintenance of telomere length is important for the preservation of vital genetic information and prevention of genomic instability. A common genetic variant in TERT, rs2736100 C/A, is ass...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Snetselaar, Reinier, van Oosterhout, Matthijs F. M., Grutters, Jan C., van Moorsel, Coline H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835035/
https://ncbi.nlm.nih.gov/pubmed/29536006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00041
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