Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease

Pulmonary fibrosis is strongly associated with telomere shortening and increased DNA damage. Key cells in the pathogenesis involve alveolar type 2 (AT2) cells, club cells and myofibroblasts; however, to what extent these cells are affected by telomere shortening and DNA damage is not yet known. We s...

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Detaylı Bibliyografya
Yayımlandı:ERJ Open Res
Asıl Yazarlar: van Batenburg, Aernoud A., Kazemier, Karin M., van Oosterhout, Matthijs F.M., van der Vis, Joanne J., Grutters, Jan C., Goldschmeding, Roel, van Moorsel, Coline H.M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: European Respiratory Society 2021
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165375/
https://ncbi.nlm.nih.gov/pubmed/34084786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00691-2020
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