Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease

Pulmonary fibrosis is strongly associated with telomere shortening and increased DNA damage. Key cells in the pathogenesis involve alveolar type 2 (AT2) cells, club cells and myofibroblasts; however, to what extent these cells are affected by telomere shortening and DNA damage is not yet known. We s...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: van Batenburg, Aernoud A., Kazemier, Karin M., van Oosterhout, Matthijs F.M., van der Vis, Joanne J., Grutters, Jan C., Goldschmeding, Roel, van Moorsel, Coline H.M.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165375/
https://ncbi.nlm.nih.gov/pubmed/34084786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00691-2020
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