Short telomere length in IPF lung associates with fibrotic lesions and predicts survival

Telomere maintenance dysfunction has been implicated in the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF). However, the mechanism of how telomere length is related to fibrosis in the lungs is unknown. Surgical lung biopsies of IPF patients typically show a heterogeneous pattern of non-fibrotic...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Snetselaar, Reinier, van Batenburg, Aernoud A., van Oosterhout, Matthijs F. M., Kazemier, Karin M., Roothaan, Suzan M., Peeters, Ton, van der Vis, Joanne J., Goldschmeding, Roel, Grutters, Jan C., van Moorsel, Coline H. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744955/
https://ncbi.nlm.nih.gov/pubmed/29281671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189467
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