Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer

Genomic technologies are reshaping the molecular landscape of colorectal cancer (CRC), revealing that oncogenic driver mutations (APC and TP53) coexist with still underappreciated genetic events. We hypothesized that mutational analysis of CRC-linked genes may provide novel information on the connec...

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書誌詳細
出版年:Oncogenesis
主要な著者: De Nicola, Francesca, Goeman, Frauke, Pallocca, Matteo, Sperati, Francesca, Pizzuti, Laura, Melucci, Elisa, Casini, Beatrice, Amoreo, Carla Azzurra, Gallo, Enzo, Diodoro, Maria Grazia, Buglioni, Simonetta, Mazzotta, Marco, Vici, Patrizia, Sergi, Domenico, Di Lauro, Luigi, Barba, Maddalena, Pescarmona, Edoardo, Ciliberto, Gennaro, De Maria, Ruggero, Fanciulli, Maurizio, Maugeri-Saccà, Marcello
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054833/
https://ncbi.nlm.nih.gov/pubmed/30032163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0066-2
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