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Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer

We have previously reported that nuclear expression of the Hippo transducer TAZ in association with Wnt pathway mutations negatively impacts survival outcomes in advanced gastric cancer (GC) patients. Here, we extended these previous findings by investigating another oncogenic cooperation, namely, t...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Pallocca, Matteo, Goeman, Frauke, De Nicola, Francesca, Melucci, Elisa, Sperati, Francesca, Terrenato, Irene, Pizzuti, Laura, Casini, Beatrice, Gallo, Enzo, Amoreo, Carla Azzurra, Vici, Patrizia, Di Lauro, Luigi, Buglioni, Simonetta, Diodoro, Maria Grazia, Pescarmona, Edoardo, Mazzotta, Marco, Barba, Maddalena, Fanciulli, Maurizio, De Maria, Ruggero, Ciliberto, Gennaro, Maugeri-Saccà, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122687/
https://ncbi.nlm.nih.gov/pubmed/30180862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1607-3
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