Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer

We have previously reported that nuclear expression of the Hippo transducer TAZ in association with Wnt pathway mutations negatively impacts survival outcomes in advanced gastric cancer (GC) patients. Here, we extended these previous findings by investigating another oncogenic cooperation, namely, t...

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Publicat a:J Transl Med
Autors principals: Pallocca, Matteo, Goeman, Frauke, De Nicola, Francesca, Melucci, Elisa, Sperati, Francesca, Terrenato, Irene, Pizzuti, Laura, Casini, Beatrice, Gallo, Enzo, Amoreo, Carla Azzurra, Vici, Patrizia, Di Lauro, Luigi, Buglioni, Simonetta, Diodoro, Maria Grazia, Pescarmona, Edoardo, Mazzotta, Marco, Barba, Maddalena, Fanciulli, Maurizio, De Maria, Ruggero, Ciliberto, Gennaro, Maugeri-Saccà, Marcello
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Commentary
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122687/
https://ncbi.nlm.nih.gov/pubmed/30180862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1607-3
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