Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression

AIMS: GTP cyclohydrolase I catalyses the first and rate-limiting reaction in the synthesis of tetrahydrobiopterin (BH4), an essential cofactor for nitric oxide synthases (NOS). Both eNOS and iNOS have been implicated in the progression of atherosclerosis, with opposing effects in eNOS and iNOS knock...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cardiovasc Res
Prif Awduron: Douglas, Gillian, Hale, Ashley B, Patel, Jyoti, Chuaiphichai, Surawee, Al Haj Zen, Ayman, Rashbrook, Victoria S, Trelfa, Lucy, Crabtree, Mark J, McNeill, Eileen, Channon, Keith M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054219/
https://ncbi.nlm.nih.gov/pubmed/29596571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy078
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