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Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension()

Overproduction of nitric oxide (NO) is thought to be a key mediator of the vascular dysfunction and severe hypotension in patients with endotoxaemia and septic shock. The contribution of NO produced directly in the vasculature by endothelial cells to the hypotension seen in these conditions, vs. the...

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Detalhes bibliográficos
Publicado no:Vascul Pharmacol
Main Authors: Chuaiphichai, Surawee, Starr, Anna, Nandi, Manasi, Channon, Keith M., McNeill, Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746318/
https://ncbi.nlm.nih.gov/pubmed/26276526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2015.08.009
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