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Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension()

Overproduction of nitric oxide (NO) is thought to be a key mediator of the vascular dysfunction and severe hypotension in patients with endotoxaemia and septic shock. The contribution of NO produced directly in the vasculature by endothelial cells to the hypotension seen in these conditions, vs. the...

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Bibliografiske detaljer
Udgivet i:Vascul Pharmacol
Main Authors: Chuaiphichai, Surawee, Starr, Anna, Nandi, Manasi, Channon, Keith M., McNeill, Eileen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746318/
https://ncbi.nlm.nih.gov/pubmed/26276526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2015.08.009
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