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Mu-opioid receptors in nociceptive afferents produce a sustained suppression of hyperalgesia in chronic pain

The latent sensitization model of chronic pain reveals that recovery from some types of long-term hyperalgesia is an altered state in which nociceptive sensitization persists but is suppressed by the ongoing activity of analgesic receptors such as μ-opioid receptors (MORs). To determine whether thes...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Severino, Amie, Chen, Wenling, Hakimian, Joshua K., Kieffer, Brigitte L., Gaveriaux-Ruff, Claire, Walwyn, Wendy, Marvizon, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053329/
https://ncbi.nlm.nih.gov/pubmed/29677019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001247
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