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Increased expression of the Cbl family of E3 ubiquitin ligases decreases Interleukin-2 production in a rat model of peripheral neuropathy

BACKGROUND: Interleukin 2 (IL-2) influences the development and severity of pain due to its antinociceptive and immunomodulatory effects. Its production is influenced by the increased expression of c-Cbl (Casitas B-lineage lymphoma proto-oncogene) and Cbl-b E3 ubiquitin ligases. We evaluated the eff...

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書誌詳細
出版年:BMC Anesthesiol
主要な著者: Jeong, Ji Seon, Kim, Ha Yeon, Shin, Byung Seop, Lee, Ae Ryoung, Yoon, Ji Hyun, Hahm, Tae Soo, Lee, Ja Eun
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052554/
https://ncbi.nlm.nih.gov/pubmed/30021515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-018-0555-z
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