The Role of E3 Ubiquitin Ligase Cbl Proteins in Interleukin-2-Induced Jurkat T-Cell Activation

Interleukin- (IL-) 2 is the major growth factor for T-cell activation and proliferation. IL-2 has multiple functions in the regulation of immunological processes. Although most studies focus on T-cell immunomodulation, T-cell activation by IL-2 is the foundation of priming the feedback loop. Here, w...

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Bibliografiske detaljer
Main Authors: Zhao, Ming-Fang, Qu, Xiu-Juan, Qu, Jing-Lei, Jiang, You-Hong, Zhang, Ye, Hou, Ke-Zuo, Deng, Hao, Liu, Yun-Peng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622291/
https://ncbi.nlm.nih.gov/pubmed/23586039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/430861
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