Expression Levels of Glycoprotein O (gO) Vary between Strains of Human Cytomegalovirus, Influencing the Assembly of gH/gL Complexes and Virion Infectivity

The tropism of human cytomegalovirus (HCMV) is influenced by the envelope glycoprotein complexes gH/gL/gO and gH/gL/UL128-131. During virion assembly, gO and the UL128-131 proteins compete for binding to gH/gL in the endoplasmic reticulum (ER). This assembly process clearly differs among strains, si...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Zhang, Le, Zhou, Momei, Stanton, Richard, Kamil, Jeremy, Ryckman, Brent J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052298/
https://ncbi.nlm.nih.gov/pubmed/29743375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00606-18
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