Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL

The core, conserved function of the herpesvirus gH/gL is to promote gB-mediated membrane fusion during entry, although the mechanism is poorly understood. The human cytomegalovirus (HCMV) gH/gL can exist as either the gH/gL/gO trimer or the gH/gL/UL128/UL130/UL131 (gH/gL/UL128-131) pentamer. One mod...

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Bibliographic Details
Published in:J Virol
Main Authors: Schultz, Eric P., Lanchy, Jean-Marc, Ellerbeck, Erin E., Ryckman, Brent J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810707/
https://ncbi.nlm.nih.gov/pubmed/26656708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01875-15
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