The Human Cytomegalovirus Protein UL116 Interacts with the Viral Endoplasmic-Reticulum-Resident Glycoprotein UL148 and Promotes the Incorporation of gH/gL Complexes into Virions

Heterodimers of glycoproteins H (gH) and L (gL) comprise a basal element of the viral membrane fusion machinery conserved across herpesviruses. In human cytomegalovirus (HCMV), the glycoprotein UL116 assembles onto gH at a position similar to that occupied by gL, forming a heterodimer that is incorp...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Siddiquey, Mohammed N. A., Schultz, Eric P., Yu, Qin, Amendola, Diego, Vezzani, Giacomo, Yu, Dong, Maione, Domenico, Lanchy, Jean-Marc, Ryckman, Brent J., Merola, Marcello, Kamil, Jeremy P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274611/
https://ncbi.nlm.nih.gov/pubmed/34011552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02207-20
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