A carregar...
Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46
Activation of protein kinase G (PKG) Iα in nociceptive neurons induces long-term hyperexcitability that causes chronic pain. Recently, a derivative of the fungal metabolite balanol, N46, has been reported to inhibit PKG Iα with high potency and selectivity and attenuate thermal hyperalgesia and oste...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052212/ https://ncbi.nlm.nih.gov/pubmed/29769318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002427 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|